We Tried Dr. Idriss’ Cult-Favorite Skincare Line—Here’s What Actually Worked

I first stumbled upon Dr. Shereene Idriss—aka PillowTalkDerm—a year or two ago through her delightfully candid skincare reviews on Instagram. She has a rare combination of expertise and honesty that immediately drew me in. As a board-certified dermatologist, she didn’t just push product trends—she broke them down, dissected the science, and helped you understand why certain ingredients worked (or didn’t).

Naturally, when she launched her own line, I was all in. This wasn’t a hype-fueled influencer drop. This was a derm-developed brand that promised smart formulations and effective results. Like thousands of others, I’d officially joined the ranks of her loyal following—aka the Skincare Nerds—and I couldn’t wait to put her products to the test.

Products I've Tried and Loved

Barrier Baste Lip Basting Duo — 10/10

This duo has been a total game-changer for my lips. The system is simple but genius: a gentle chemical exfoliating peel followed by a deeply hydrating balm. The peel uses a roller ball applicator that glides on smoothly, instantly sloughing away dry, flaky skin. And yes—it somehow makes my lips look plumper in the process, likely thanks to the ultra-smooth finish.

The balm is thick, cushiony, and packed with nourishing ingredients. It leaves a beautiful soft pink tint and a hint of minty freshness. I love how long it lasts and how healthy my lips look throughout the day. It’s not just another balm—it’s a complete lip treatment.

Before this product, I assumed my constantly chapped lips were just part of life. Turns out, I was just missing the right routine. The only caveat? The peel has a slightly acidic taste, so I don’t recommend applying it right before eating or drinking.

Why she made it: During a trip to Jackson, WY, Dr. Idriss found that even her favorite lip balms weren’t cutting it in the dry, cold climate. That’s when she realized hydration wasn’t enough—she needed exfoliation first. The result? Her now-viral two-step lip basting method.

Star Ingredients:

Peel: Mandelic Acid, Gluconolactone, Glycerin (gentle exfoliants that remove dead skin without irritation)

Balm: Squalane, Ceramide III, Oat Oil, Shea Butter (to seal in moisture and repair the barrier)

Clinical Study: 100% of participants reported relief from dryness and flakiness after just one use.

The Depuffer — 8.5/10

This little tube packs a big punch. The metal rollerball applicator delivers an immediate cooling sensation that’s incredibly soothing—like a jade roller with benefits. It glides over the skin and gives a mini facial massage that feels luxe and de-stressing, especially first thing in the morning.

I was especially impressed by the inclusion of arnica, which has always been my go-to for calming redness. Combined with niacinamide, centella asiatica, and azelaic acid, the formula really does calm irritation and reduce puffiness. The one drawback? Dispensing the right amount can be tricky, and applying too much leaves a slight film.

Why it works: The roller tool enhances circulation and product absorption, while the formula targets redness, swelling, and inflammation.

Bonus: It won Allure’s Best of Beauty Award in 2023.

Clinical Results: 92% of testers saw reduced redness within five minutes of application.

Major Fade Hyper Serum

Of all the brightening serums I’ve used, this one might be the most elegant. It delivers a dewy, radiant glow that feels like it’s coming from within—not just sitting on top of your skin. I especially love the packaging: a dual-cartridge system that protects the formula from air and light, which helps maintain potency.

The texture is silky and sinks in beautifully. After a few weeks, my skin looked noticeably more even and luminous. It’s quickly become a staple in my nighttime routine.

Hero Ingredients: Vitamin C, Tranexamic Acid, Niacinamide

What reviewers say: People love the lightweight texture and consistent brightening results. It's also praised for evening out tone over time.

Final Thoughts

Dr. Idriss Skincare is more than just another trendy brand—it’s a science-first, education-driven line that truly delivers on its promises. With thoughtful formulations, empowering messaging, and a mission rooted in transparency and accessibility, it’s no wonder this brand is quickly becoming a skincare staple for Gen-Z and Millennial consumers alike.

If you’re looking for effective solutions to hyperpigmentation, dullness, or just want to support a brand founded by a badass female dermatologist who keeps it real, Dr. Idriss deserves a spot in your top shelf.

✨ Splendid Shopper Approved ✨